Walsh Moore is a lifelong St. Louisan. She grew up in Kirkwood and graduated from Ursuline Academy. At Bradley University, she studied Arabic and International Relations and spent one semester at The American University in Cairo, Egypt, immersing herself in one of the world's largest cities and its role as a trade hub between Africa, Asia, and Europe. She graduated as a member of the International Relations Honor Society and later earned her Chancellor's Certificate in International Trade from the World Trade Center through a joint program with the University of Missouri-St. Louis.

Walsh Moore worked in manufacturing and became a founding member of the North Broadway Business Development Association. She later worked as a customs brokerage agent, where she navigated the steel tariffs and import legalities of Chinese products during the beginning of the COVID-19 outbreak. She also created and managed several foreign trade zones for major Missouri companies.

Walsh Moore is a proud member of the St. Louis Metropolitan St. Patrick's Day Parade, an organization that was founded in part by her grandparents. She is the founder and Co-Chair of the American Irish State Legislators Caucus. In 2023, she was invited to address the Irish Parliament in her role with the organization.

Walsh Moore plays an active role in several community organizations, including the Great Rivers Environmental Law Center, the North Broadway Business Development Community, the Disabled Athletes Sports Association, and the Progressive Democrats of Lemay. Additionally, she serves as co-chair of the Sportsman's Caucus in the Missouri House.

Walsh Moore lives in South St. Louis County with her husband, Greg Moore, and the couple welcomed their first child in 2021. She is also a proud cancer survivor.